A novel cell death gene acts to repair patterning defects in Drosophila melanogaster.
نویسندگان
چکیده
Cell death is a mechanism utilized by organisms to eliminate excess cells during development. Here, we describe a novel regulator of caspase-independent cell death, Mabiki (Mabi), that is involved in the repair of the head patterning defects caused by extra copies of bicoid in Drosophila melanogaster. Mabiki functions together with caspase-dependent cell death mechanisms to provide robustness during development.
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ورودعنوان ژورنال:
- Genetics
دوره 197 2 شماره
صفحات -
تاریخ انتشار 2014